If there is inductance in the output, an open circuit (actually probably seen as a capacitance) might cause an inductive spike or even a resonant circuit where high voltages may be produced. Once it starts to break down components, things could go south in a hurry. But that would indicate a poor design or a component failure to start with. A battery charger should be able to tolerate anything from an open circuit to a short circuit, as well as some inductance and capacitance.
I just looked at the charger information at
http://www.manzanitamicro.com/downlo...ry/15-chargers, and it seems that they can be used for anything from 12V to 450V output. So if they have an internal bus of 180 or 360 VDC, they must use some sort of buck/boost topology which involves an inductor and a high frequency PWM. But the "potential" is there for the full high voltage to be applied to the battery pack until the regulation kicks in. Apparently you can adjust the output over this wide range to match your battery pack, and there is always the chance that the voltage or current settings were incorrect. And a true current mode regulator will use all of its DC bus voltage in an attempt to get the charge current needed. The specs say it starts in current mode and then switches to voltage mode, so unless it also has a voltage limiter it would apply up to 450 V to the pack with an open cell. And that might be bad...