When repurposing a rear-diff as a simple reduction gearbox...
Does that imply just direct driving a RWD car, or, are some of you suggesting taking one and just mounting it for a FWD?
This approach has been used for FWD, but in this case DrGee is talking about a 4WD vehicle which comes with similar final drive units at front and rear.
To get a reduction, do you need to be at 90 degrees from the input? (I.E. mount the motor vertically or, I guess torpedo-wise rather than sideways & horizontal?).
The input shaft (propeller shaft) to the rear of a front-engine vehicle is obviously 90 degrees to the axle, and in a typical 4WD system with a longitudinal engine the same is true of the front (the front propeller shaft is running forward from the transfer case which is in the middle of the vehicle).
No common final drive unit will be designed for a vertical input shaft, although some DIY builders have apparently planned to - and even built - vehicles with the final drive rotated to place the shaft of an attached motor vertically. This is a bad idea in multiple ways.
A final drive with a transverse input will normally be part of a transaxle, so you wouldn't likely use it unless you were using the the transmission as well. There are lots of 4WD (AWD) vehicles with a transverse engine, and converting them while using the final drives would presumably mean using the transmission as well, and a single motor.
I presume for FWD you're lopping off the axle parts and then, somehow joining those to your CVs?
Front axle parts are similar to rear axle parts from a vehicle with independent rear suspension, although outer joints may be a different type of CV (for greater angular capability at the front), and shaft lengths are usually very different left to right in the front of a 4WD system (because the final drive sits to one side of the engine).
For bonus confusion, the output of the final drive which passes under the engine sometimes goes right through the engine crankcase, and even if it is separate it is usually in a fixed tube so that the inner CV joint is on the opposite side of the engine from the differential.
For DrGee this is not an issue, as he would use the complete final drive and axles that come with the vehicle (as long as the housing can be separated from the engine). If adding this style of final drive to a vehicle which had a different system, custom axles would be needed (a common conversion challenge).