Why would you make a series hybrid out of a transmission which is already - in its stock form - an advanced power-split hybrid system? Why not just connect the motorcycle engine to the L110 (from GS 450h) input? 
A series hybrid system will be less efficient, and more difficult to control, but of course you can do it. You're just duplicating the usual engine-driven generator set configuration, but with a ~300 V generator (the obvious source is any EV drive motor that is handy and for which you can get a controller). This is not normally sold as a ready-to-use package (because no one needs a 300 V DC generator set), but to use the motorcycle engine you're not looking for a complete set anyway. Typical "inverter" generator sets produce high-frequency high voltage DC from the generator, and rectify then invert that to produce 120 V or 240 V AC; the control system for both engine and inverter is one package specifically intended for these generator sets.
A series hybrid system will be less efficient, and more difficult to control, but of course you can do it. You're just duplicating the usual engine-driven generator set configuration, but with a ~300 V generator (the obvious source is any EV drive motor that is handy and for which you can get a controller). This is not normally sold as a ready-to-use package (because no one needs a 300 V DC generator set), but to use the motorcycle engine you're not looking for a complete set anyway. Typical "inverter" generator sets produce high-frequency high voltage DC from the generator, and rectify then invert that to produce 120 V or 240 V AC; the control system for both engine and inverter is one package specifically intended for these generator sets.